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Effect of Garambullo (Myrtillocactus geometrizans) Consumption on the Intestinal Microbiota Profile in an Early-Phase Rat Model of Colon Cancer

Article2026

Sánchez-Recillas E., Almanza-Aguilera E., Bars-Cortina D., Zamora-Ros R., Godínez-Santillán R. I., Sánchez-Tusié A. A., Vergara-Castañeda H. A., Effect of Garambullo (Myrtillocactus geometrizans) Consumption on the Intestinal Microbiota Profile in an Early-Phase Rat Model of Colon Cancer, International Journal of Molecular Sciences, 2026, 27(2):1014, doi: 10.3390/ijms27021014

An experiment in male rats compares the microbiota after administration of freeze-dried Myrtillocactus geometrizans fruit and an extraction residue in an AOM/DSS model. Sequencing of 16S rRNA gene fragments revealed time-dependent differences in the representation of selected bacterial genera. Alpha-diversity indices did not differ significantly between groups at the same time points. Small groups and the reported pooling of DNA constrain interpretation, and short-chain fatty acids were not measured in this paper.

Biotechnology and applicationsMyrtillocactus

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